This reaction takes place through the addition of unsaturated hydrocarbons or by substitution of acidic hydrogen using a chloralkyl compound.

Typical alkylation reactions with unsaturated hydrocarbons that have been successfully carried out in the loop reactor are:

  • Phenol and Isobutylene to p-Tertiarybutylphenol
  • Phenol and Isobutylene to 2,4 or 2,6 Ditertiarybutylphenol
  • Phenol and n-Butene to 2-Secondarybutylphenol
  • O-Toluidine and Ethylene to Methylethylaniline

Typical alkylation reactions with alkylchlorides that have been successfully carried out in the loop reactor are:

  • P-Nitrophenol and Methylchloride to p-Nitrophenetol
  • Theophyllin sodium and Methylchloride to Coffein

The primary HH Loop Reactor advantages are:

  • high mass transfer rates
  • Reduced overall reaction time
  • High conversion rates
  • Batch reproducibility