Typically this reaction involves the selective substitution of a halogen bond to an organic compound by reacting with ammonia at moderate temperatures and pressures. The primary HH Loop Reactor advantages are the high mass transfer rates and the safety aspects such as no sparks formation in the headspace of the reactor.

Additional advantages are:

  • Reduced overall reaction time
  • High yields
  • Batch reproducibility
  • High heat removal capacity

Typical amination reactions that have been successfully carried out in the loop reactor are as follows:

  • o-chloronitrobenzene to o-nitroaniline
  • 3,4 dichloronitrobenzene to 2-chloro-4-nitroaniline
  • Myristilic Acid and Dimethylamine to Dimethylalkylamine
  • 2,6-Disulphonic acid-anthraquinone to 2,6-Diaminoanthraquinone